|
|
|
RICT 2010 - Interfacing Chemical Biology and Drug Discovery |
| 30/06/2010 |
| Target Selection: Hit to Lead: Identification, development |
|
| 08:00 | Registration |
|
| 09:30 | Opening |
|
| Session Chair |
Prof. André TARTAR
(UNIVERSITY LILLE 2, Lille, France) |
| 10:00 | Vascular Tumor Targeting |
Prof. Dario NERI
(ETH ZÜRICH, Zürich, Switzerland) |
| 10:45 | Coffee Break |
|
| Session Chair |
Dr Marcel HIBERT
(FACULTE DE PHARMACIE, Illkirch, France) |
| 11:15 | Novel Antagonists of Protease Activated Receptors 1: Unusual GPCRs Implicated in Cardiovascular Diseases |
Dr Michel PEREZ
(PIERRE FABRE, Toulouse, France) |
| 12:00 | Identification of Functionally Selective Alpha2C-AR Agonists as Potential New Drugs for Treatment of Pain |
Dr Eric JNOFF
(UCB PHARMA SA, Braine-l'Alleud, Belgium) |
| 12:45 | Lunch and Poster Session |
|
| Session Chair |
Dr. Robert H. DODD
(ICSN CNRS, Gif-Sur-Yvette, France) |
| 14:15 | Pyrrolopyrimidine-Based P2X3 Antagonists for the Treatment of Pain |
Dr Louis-David CANTIN
(ASTRAZENECA R&D, Montréal, Canada) |
| 15:00 | Binding of the Macrocyclic Noncovalent Inhibitor TMC435 to its HCV NS3/NS4A Protease Target |
Dr Max CUMMINGS
(TIBOTEC, Mechelen, Belgium) |
| 15:45 | Coffee Break and Poster Session |
|
| Session Chair |
Dr Luc VAN HIJFTE
(JANSSEN RESEARCH & DEVELOPMENT, Illkirch, France) |
| 16:30 | Indole-carboxylic Acid Amides as Novel CETP Inhibitors: From Hit to Clinical Candidate and Beyond |
Dr Philippe PFLIEGER
(F. HOFFMANN-LA ROCHE LTD, Basel, Switzerland) |
| 17:15 | Inhibitors of PKC-beta and GSK-3beta: A Tale of Two Kinases |
Dr Bruce MARYANOFF
(SCRIPPS, San Diego, United States) |
| 18:30 | Cocktail and Poster Session
(Faculty of Pharmacy) |
|
| 01/07/2010 |
Section A
Synthetic Chemistry: new frontiers impacting drug discovery | Section B
Screening, managing structure-properties relationship |
| |
| Session Chair |
Dr Maurice MEDEBIELLE
(UNIVERSITÉ CLAUDE BERNARD LYON 1, Villeurbanne, France) |
| 09:00 | Hybrids Natural Products with Neurotrophin Activity |
Dr Bruno FIGADERE
(UNIVERSITÉ PARIS-SUD, Chatenay-Malabry, France) |
| 09:45 | Two Stimulating Concepts in Natural Substances Synthesis: the NEO Cascade and the CIM Strategy |
Prof. Arnaud HAUDRECHY
(UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE, Reims, France) |
| 10:30 | Coffee Break |
|
| Session Chair |
Dr Pascal GEORGE
(SANOFI-AVENTIS R&D, Longvilliers, France) |
| 11:00 | New Methods for Peptide Synthesis |
Prof. David CRICH
(ICSN, Gif-sur-Yvette, France) |
| 11:45 | Peptidomimetic Foldamers: Connecting Structure to Function |
Dr Gilles GUICHARD
(THE EUROPEAN INSTITUTE OF CHEMISTRY AND BIOLOGY (IECB), Pessac, France) |
| 12:30 | Lunch and Poster Session |
|
| Session Chair |
Dr Bruno FIGADERE
(UNIVERSITÉ PARIS-SUD, Chatenay-Malabry, France) |
| 14:00 | Active Pharmaceutical Ingredients in Convergent Technologies: How Are They Chosen |
Dr Cynthia MARYANOFF
(CORDIS, A JOHNSON AND JOHNSON COMPANY, Spring House, United States) |
| 14:45 | Fragment-based Design of Small RNA Binders |
Dr Laurent MICOUIN
(UNIVERSITÉ PARIS DESCARTES, Paris, France) |
|
| Session Chair |
Prof. Hervé GALONS
(SCT & PARIS DESCARTES UNIVERSITY, Paris, France) |
| 09:00 | Carbonic Anhydrases: Novel Therapeutic Applications for Inhibitors and Activators |
Prof. Claudiu SUPURAN
(UNIVERSITY OF FIRENZE, Sesto Fiorentino, Italy) |
| 09:45 | Prodrug Approaches for Enhancing the Bioavailability of Drugs |
Prof. Christa MÜLLER
(UNIVERSITY OF BONN, Bonn, Germany) |
| 10:30 | Coffee Break |
|
| Session Chair |
Dr Philippe PITCHEN
(FOREST RESEARCH INSTITUTE, Hauppauge, United States) |
| 11:00 | Functional Assays as Multifaceted Tools for HTS |
Dr Olivier NOSJEAN
(SERVIER RESEARCH INSTITUTE, Croissy-sur-Seine, France) |
| 11:45 | Virtual Screening in Drug Discovery: Overview and Applications |
Dr Romano KROEMER
(SANOFI AVENTIS, Vitry sur Seine, France) |
| 12:30 | Lunch and Poster Session |
|
| Session Chair |
Prof. Olivier DUVAL
(UNIVERSITÉ D'ANGERS, Angers, France) |
| 14:00 | Topically Bioavailable and Systemically Safe PPARγ Agonists as Sebum Modulators |
Dr Jean-Guy BOITEAU
(GALDERMA R&D, Sophia-Antipolis, France) |
| 14:45 | Novel Compound Classes as Calcilytics for the Treatment of Osteoporosis |
Dr Leo WIDLER
(NOVARTIS, Basel, Switzerland) |
|
|
| Session Chair |
Prof. Dario NERI
(ETH ZÜRICH, Zürich, Switzerland) |
| 16:00 | Sugars and Proteins |
Prof. Ben DAVIS
(OXFORD UNIVERSITY, Oxford, United Kingdom) |
| 16:45 | End of Conference |
|
| 17:15 | Departure by bus to visit the “Taittinger wine cellars” (for pre-registrated participants) |
|
| 17:30 | Visit of "Caves Taittinger" |
|
| 20:00 | Banquet |
|
| 20:00 | Banquet in the “Demeure des Comtes de Champagne” (18-22 rue de Tambour, 511100
Reims, near the City Hall) |
|
| In parallel:
14:00-15:30 - JOB Forum |
Dr Patrick PLE (ASTRA ZENECA, Reims, France)
Dr Laurent JEANNIN (SOLVAY, Belgium)
Mr Térence BEGHYN (UNIVERSITY LILLE 2, Lille, France) |
| 02/07/2010 |
| Case-Studies from Bench to Bedside |
|
| Session Chair |
Dr Edmond DIFFERDING
(DIFFERDING CONSULTING, Louvain-la-Neuve, Belgium) |
| 09:00 | The First NO- and Heam-independent Activator of Soluble Guanylate Cyclase for the IV Treatment of Acute Heart Failure |
Dr Michael G. HAHN
(BAYER HEALTHCARE, Wuppertal, Germany) |
| 09:45 | A Single Synthetic Peptide for Immunomodulating Lupus, a Complex Autoimmune Disease |
Dr Sylviane MULLER
(IBMC-CNRS, Strasbourg, France) |
| 10:30 | Coffee Break |
|
| Session Chair |
Dr Dominique LESUISSE
(SANOFI AVENTIS, Chilly-Mazarin, France) |
| 11:00 | The Identification of Selective p38 MAPK Inhibitors with High Blood Potency Suitable for Clinical Development: The Discovery of Losmapimod
|
Dr Vipul K. PATEL
(GLAXOSMITHKLINE, Stevenage, United Kingdom) |
| 11:45 | Telbivudine, a Potent and Specific Anti-HBV Nucleoside Analogue: From the Bench to its Marketing Approvals (Tyzeka®, Sebivo®) |
Dr Gilles GOSSELIN
(IDENIX SARL, Montpellier, France) |
| 12:30 | Discovery of Inhibitors of MAPKAPK5, a Novel Target for Rheumatoid Arthritis |
Dr Martin ANDREWS
(GALAPAGOS NV, Mechelen, Belgium) |
| 13:15 | Conclusions
End of the Symposium |
|
| <Previous page |
