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EFMC 2nd Short Course on Medicinal Chemistry |
11/04/2010 |
18:00 | Dinner |
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19:30 | Introduction to Safety & Attrition Workshop |
Dr Alan STOBIE (PFIZER, Sandwich, United Kingdom) |
21:00 | Close |
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12/04/2010 |
08:30 | General Overview of Current Safety and Toxicity Testing |
Dr Dominic WILLIAMS (UNIVERSITY OF LIVERPOOL, Liverpool, United Kingdom) |
10:30 | Coffee Break |
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11:00 | Small Molecule Based Attrition (1) - Structural 'Alerts' |
Dr Julian BLAGG (THE INSTITUTE OF CANCER RESEARCH, Surrey, United Kingdom) |
12:30 | Lunch |
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13:30 | Small Molecule Based Attrition (2) - Molecular Properties |
Dr Julian BLAGG (THE INSTITUTE OF CANCER RESEARCH, Surrey, United Kingdom) |
15:30 | Tea Break |
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16:00 | Off-Target Based Attrition (1) - Ion Channel Safety |
Dr Chris POLLARD (ASTRAZENECA, Macclesfield, United Kingdom) |
18:00 | Close |
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19:30 | Dinner |
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13/04/2010 |
08:30 | Off-Target Based Attrition (2) - Role of Transporter Interactions in Toxicology and Attrition |
Dr Gerry KENNA (ASTRAZENECA, Macclesfield, United Kingdom) |
10:00 | Coffee Break |
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10:30 | Admet or DMPK Based Attrition |
Dr Don WALKER (PFIZER, Sandwich, United Kingdom) |
12:30 | Lunch |
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13:30 | Choosing the Right Target |
Dr Alan STOBIE (PFIZER, Sandwich, United Kingdom) |
13:30 | Attrition (3) - Insilico Prediction Methods |
Dr Alan STOBIE (PFIZER, Sandwich, United Kingdom) |
14:30 | The Safety and Attrition Game |
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18:00 | Close |
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19:30 | Dinner |
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14/04/2010 |
08:30 | Newer Methods of Predicting Toxicity (1) - Characterising Mechanisms of Toxicity |
Dr Mark M. GOSINK (PFIZER, Groton, United States) |
10:00 | Coffee Break |
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10:30 | Newer Methods of Predicting Toxicity (2) - Use of Whole Cell Invitro Methods |
Dr Jim DYKENS (PFIZER, Sandwich, United Kingdom) |
12:30 | Lunch |
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13:30 | Course Ends |
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