Dr Anthony WOOD (PFIZER, Cambridge, United States)
08:30
Opening
09:00
Maitotoxin. An Inspiration for Synthesis
Prof. K.C. NICOLAOU (THE SCRIPPS RESEARCH INSTITUTE & UNIVERSITY OF CALIFORNIA, Houston, United States)
09:50
Tofacitinib (CP-690,550): Discovery of a Potent and Selective JAK Inhibitor
Dr Mark FLANAGAN (PFIZER, Connecticut, United States)
10:30
Coffee Break and Exhibition
11:00
A few of my Favorite Rings: Catalysis Inspired by Lactones and Lactams
Prof. Vy M. DONG (UNIVERSITY OF TORONTO, Toronto, Canada)
11:50
Small Molecules Inhibitors of the WNT Signalling Pathway with Potential Applications in Oncology
Dr Alessandro PADOVA (SIENA BIOTECH, Siena, Italy)
12:30
Lunch and Exhibition
Session Chair
Dr Nikolai KUZNETSOV (INEOS RAS, Moscow, Russia)
14:00
Drug Discovery by Programmed Self-Assembly
Prof. Nicolas WINSSINGER (UNIVERSITY OF STRASBOURG, Geneva, Switzerland)
14:50
The Many Uses of Noncovalent Mass Spectrometry in Early-stage Drug Discovery
Dr Jean-Paul RENAUD (NOVALIX, Ostwald, France)
15:30
Small Molecule Inhibitors of the Neuropilin-1 VEGF-A Interaction
Dr Philip FALLON (DOMAINEX, Saffron Walden, United Kingdom)
15:45
Lead identification of a new class of P2Y12 inhibitors "From a low active and insoluble HTS hit to soluble and active lead compounds"
Mr Fredrik ZETTERBERG (ASTRAZENECA, Gothenburg, Sweden)
16:00
Coffee Break, Exhibition and Posters
16:30
GPR119: Knowledge Based Lead Identification
Dr Sherrie L. PIETRANICO-COLE (ROCHE, NUTLEY NJ, United States)
17:10
Regioselective Reactions on a Chiral Substrate Controlled by the Configuration of a Chiral Catalyst
Prof. Henri KAGAN (UNIVERSITY PARIS-SUD 11, ORSAY Cedex, France)
18:00
Closing of the Day
18:30
City Tour for Participants
23/08/2011
Session Chair
Dr Christophe GENICOT (UCB SA, Braine-l'Alleud, Belgium)
08:30
Synthesis of Marine Polyketides as Promising Anticancer Agents
Prof. Ian PATERSON (CAMBRIDGE UNIVERSITY, Cambridge, United Kingdom)
09:20
Chemical Probes for Epigenetics
Dr Mark BUNNAGE (PFIZER, Boston, United States)
10:00
The Chemical Biology Consortium-
and Experimental Therapeutics Program
Dr Sanjay MALHOTRA (NATIONAL CANCER INSTITUTE, Frederick, United States)
10:15
Coffee Break, Exhibition and Posters
10:45
Design Strategy for Preparation of Drug-like Polyheterocycles with Privileged Substructures for Discovery of Specific Small Molecule Modulators
Prof. Seung Bum PARK (SEOUL NATIONAL UNIVERSITY, Seoul, Korea, South)
11:35
Bromodomains a New Class of Epigenetic Targets Ripe for Small Molecule Drug Discovery
Dr Jason WITHERINGTON (GLAXOSMITHKLINE R&D, Stevenage, United Kingdom)
12:15
Identification of Leads from the Tres Cantos Antimalarial Set: Cyclopropyl Carboxamides Show Good Oral Bioavailability and Efficacy In Malarial Animal Models
Mrs Maria Lourdes RUEDA-BENEDE (GLAXOSMITHKLINE, Tres Cantos, Spain)
12:30
Lunch and Exhibition
13:15
Poster Session 1
Session Chair
Prof. Gerhard ECKER (UNIVERSITY OF VIENNA, Vienna, Austria)
14:15
Minor Enantiomer Recycling –
A Strategy for Improving Enantioselectivity
Prof. Christina MOBERG (KTH SCHOOL OF CHEMICAL SCIENCE AND ENGINEERING, Stockholm, Sweden)
15:05
Antibody Directed Cytotoxics
Prof. John FLYGARE (GENENTECH, California, United States)
15:45
Exploring the Rigid Mono- and Diamine Chemical Space
Dr Dmytro VOLOCHNYUK (ENAMINE LTD., Kiev, Ukraine)
16:00
Highly Efficient Catalytic System for C-H Activation: A Novel and Practical Synthesis of Angiotensin II Receptor Blockers
Dr Masahiko SEKI (MITSUBISHI TANABE PHARMA CORPORATION, Fukuoka, Japan)
16:15
Coffee Break, Exhibition and Posters
16:45
Bicyclic Peptides with Tailored Binding Specificities for Therapeutic Application
Prof. Christian HEINIS (ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL), Lausanne, Switzerland)
17:05
Adventures in Medicinal Chemistry and Knowledge Capture
Dr Alexander MAYWEG (F. HOFFMANN-LA ROCHE LTD, BASEL, Switzerland)
17:25
Target Synthesis Directed Methodology Development
Prof. Dawei MA (SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, Shanghai, China)