Prof. Vincent LISOWSKI (UNIVERSITÉ DE MONTPELLIER 1, Montpellier, France)
14:15
A Look at Some Innovative Chemical Aspects in Medicinal Chemistry, about Heterocycles, Microwaves, Chemical Libraries, Boronics and Garlands Paul Ehrlich Prize Lecture
Dr Luc VAN HIJFTE (JANSSEN RESEARCH & DEVELOPMENT, Illkirch, France)
09:00
JNJ-42153605: A Novel Positive Allosteric Modulator of mGluR2 for the Treatment of CNS Disorders
Dr Jose CID (JANSSEN RESEARCH AND DEVELOPMENT, Toledo, Spain)
09:45
Progress on Allosteric Modulation of mGluR5 and mGluR4: towards New Treatment Paradigms in Parkinson’s Disease
Dr Jean-Philippe ROCHER (ADDEX THERAPEUTICS, Plan-les-Ouates, Switzerland)
Session Chairman
Prof. Dario NERI (ETH ZÜRICH, Zürich, Switzerland)
09:00
A Yeast-based Model for Prion Disease Allowed Isolation of Specific and Competitive Inhibitors of a New Protein Chaperone Activity Borne by the Ribosome that are Active Against Other Amyloid-based Diseases
Prof. Marc BLONDEL (INSERM, Brest, France)
09:45
Structure and Function of Acid-Sensing Ion Channels
Dr Stephan KELLENBERGER (UNIVERSITÉ DE LAUSANNE, Lausanne, Switzerland)
10:30
Coffee Break and Poster Session
Session 6: Epigenetics
Session 7: New Tools / Platforms
Session Chairman
Prof. Yves CENATIEMPO (UNIVERSITÉ DE POITIERS, Poitiers Cedex, France)
11:00
DNA Methylation Inhibitors In Cancer: Recent and Future Approaches
Dr Paola ARIMONDO (CNRS - PIERRE FABRE, Toulouse, France)
11:45
From ApoA1 Upregulation to BET Family Bromodomain Inhibition: Unlocking the Potential of an Epigenetic Target Class
Dr Olivier MIRGUET (GLAXOSMITHKLINE, Les Ulis, France)
Session Chairman
Dr Olivier LAVERGNE (., Les Ulis, France)
11:00
Accelerating Drug Discovery through High Throughput Medicinal Chemistry -
Alternative Lead Finding & Optimisation Approaches Including Representative Project Examples
Dr Werngard CZECHTIZKY (SANOFI, Frankfurt am Main, Germany)
11:45
Combined Use of Noncovalent Mass Spectrometry and Other Biophysical Techniques in Early-stage Drug Discovery
Dr Jean-Paul RENAUD (NOVALIX, Ostwald, France)
12:30
Lunch and Poster Session
Session 8: Exploring Chemical Space-Fragments
Session 9: Case Studies (CNS)
Session Chairman
Prof. Janos SAPI (SCT & UNIVERSITY OF REIMS-CHAMPAGNE-ARDENNE, Reims, France)
14:00
Pharmacophore-based Parallel in Silico Screening: An Interesting Concept for Efficient Activity Profiling in Drug Discovery
Prof. Dr Thierry LANGER (PRESTWICK CHEMICAL, Vienna, Austria)
14:45
Reduce to the Max – Probing Biology with Natural Product Fragments
Prof. Karl GADEMANN (UNIVERSITY OF ZURICH, Zurich, Switzerland)
15:30
Chemical space exploration via Natural Product-like compounds
