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Confirmed Plenary Speakers (to Date)
Applying CRISPR/CAS9 For Cancer Target Identification, Validation and Novel Treatment Combinations
 | Dr Roderick BEIJERSBERGEN (NETHERLANDS CANCER INSTITUTE, Amsterdam, The Netherlands) Read more
Name:
Roderick L Beijersbergen PhD
Title:
Associate Professor and Director NKI Robotics and Screening Center
Research field:
Functional Genomics in Oncology
Education:
Biomedical Sciences, Leiden University
PhD Utrecht University
Former Professional experience:
AvL fellow The Netherlands Cancer Institute
Postdoctoral Fellow with Prof. RA Weinberg, Whitehead Institute for Biomedical Research, USA
Postdoctoral fellow with Prof. R Bernards, The Netherlands Cancer Institute
Research Associate, Harvard University, USA
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Use of Cyclic Dinucleotides (CDNs) to Induce Stimulator of Interferon Genes (STING)-Dependent Antitumor Immunity
 | Dr Cedric BOULARAN (INVIVOGEN, TOULOUSE, France) Read more
Cedric Boularan is currently a Research Investigator at InvivoGen in Toulouse (France). He obtained his PhD in Cochin Institute (Paris), moved to a postdoctoral fellowship at the National Institutes of Health (Bethesda, MD) and then to Lifesearch, a biotech company. His research focused on in vitro and in vivo evaluation of mechanism regulating GPCR function for oncology, cardiology or immunology fields. His work has been published in major journals. He joined InvivoGen R&D department in 2015 to emphasize the preclinical proof of concept to use innate immune ligands (especially STING agonists) as onco-immuno-modulator. Close window
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Synthetic Genetics: Beyond DNA and RNA
 | Dr Philipp HOLLIGER (MRC LABORATORY OF MOLECULAR BIOLOGY, Cambridge, United Kingdom) Read more
Philipp Holliger is a Program Leader at the MRC Laboratory of Molecular Biology (LMB) in Cambridge, UK. Phil graduated from the Swiss Federal Institute of Technology (ETH) Zürich with Steven A Benner. He then moved to Cambridge for a Ph.D. and a postdoctoral fellowship with Sir Gregory Winter. In 2000, he joined the faculty at the LMB where he was tenured in 2005.
His research spans the fields of chemical biology, synthetic biology and in vitro evolution. His work has been published in major journals (e.g. Nature, Science, Cell etc.) and has led to numerous patents. His recent work, describing a range of novel synthetic genetic polymers (XNAs) was featured in Scientific American’s 10 World Changing Ideas (2012). He is a member of the European Molecular Biology Organization (EMBO) and a consultant to several successful biotech companies including Cambridge Antibody Technology / Medimmune, Solexa / Illumina, Domantis and GSK.
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2’-Spiro-substituted Nucleosides Active against the Hepatitis C-virus
 | Dr Tim JONCKERS (JANSSEN INFECTIOUS DISEASES-DIAGNOSTICS BVBA, Beerse, Belgium) Read more
After obtaining his Ph.D. in Organic Chemistry from the University of Antwerp in 2003, Tim joined the Medicinal chemistry department of Tibotec, a Johnson & Johnson affiliate. In 2010, the Tibotec team moved to Janssen Pharmaceutica in Beerse, Belgium. Currently, he is Scientific Director at Janssen and holds the position of Head of Medicinal Chemistry, Infectious Diseases. His main research focus is the identification of new small molecule inhibitors -including novel nucleoside derivatives- useful for the treatment of viral diseases. Close window
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Discovery of Novel DOT1L Inhibitors by Fragment Growing, Defragmentation and Fragment Linking
 | Dr Henrik MOEBITZ (NOVARTIS, Basel, Switzerland) Read more
Henrik Möbitz is currently group leader and Senior Research Investigator, Global Discovery Chemistry at Novartis. In this role, he has lead medicinal chemistry projects and external collaborations. Prior to this, he studied enzyme mechanisms by use of biochemistry (PhD at Albert-Ludwigs-Universität Freiburg in 2003) and simulation (Postdoctoral Fellow at UC Santa Barbara). Recent research projects target epigenetic methyl transferases, helicases, kinases and the MAPK pathway in particular, by integrating structure based design and data analysis. Close window
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Local Target Structure Influences the Efficacy of Oligonucleotide-based Drugs
 | Prof. Georg SCZAKIEL (UNIVERSITY OF LÜBECK, Lübeck, Germany) Read more
Prof. Dr. Georg Sczakiel, Director of the Institute of Molecular Medicine ,University of Luebeck, Germany
Research areas: Antisense nucleic acids, oligonucleotide-based drugs, RNA-RNA interactions, delivery, intracellular trafficking, RNA-based non-invasive diagnostics, urine RNA
Diploma in Chemistry (University of Freiburg), Ph.D. in Molecular Biology (Max-Planck-Institute, Heidelberg), Habilitation in Theoretical Medicine (German Cancer Research Center, Heidelberg), Post-Doc in Tsukuba and Tokyo (Japan), Project leader, Steinbeis Transfer Center for Genome Informatics (Heidelberg)
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