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Monday June 23, 2014 |
09:00 | Opening Ceremony |
Marianne FILLET (UNIVERSITY OF LIEGE, Liege, Belgium) Jacques CROMMEN (UNIVERSITY OF LIEGE, Liege, Belgium) |
| Session chairs: |
Coral BARBAS (SAN PABLO - CEU UNIVERSITY, Madrid, Spain) Marianne FILLET (UNIVERSITY OF LIEGE, Liege, Belgium) |
09:30 | Building on Success - Metabolic Profiling for Patients and Populations |
Ian D. WILSON (IMPERIAL COLLEGE LONDON, London, United Kingdom) |
10:10 | Towards Personalised Medicine Based on Metabolomics with Mass Spectrometry |
Guowang XU (DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES, Dalian, China) |
10:50 | Coffee Break |
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Session 1 | Session 2 |
| Session chairs: |
Robert KENNEDY (UNIVERSITY OF MICHIGAN, Michigan, United States) Guowang XU (DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES, Dalian, China) |
11:10 | Nanoimmunoaffinity Extraction and Analysis of Biomarkers of Oxidative Stress |
Michael LÄMMERHOFER (EBERHARD KARLS UNIVERSITY TÜBINGEN, Tübingen, Germany) |
11:40 | Microflow LC-MS/MS of Human Osteopontin Using an Extended Peptide Internal Standard to Track Digestion and Immunocapture Variability |
Thomas KARNES (VIRGINIA COMMONWEALTH UNIVERSITY, Richmond, Virginia, United States) |
12:00 | Antibody-Free Bioanalysis of Proteins and Peptides in Complex Body Fluids at The PM Level By LC-MS/MS |
Rainer BISCHOFF (UNIVERSITY OF GRONINGEN, Groningen, The Netherlands) |
12:20 | Investigations of Metalloproteins and their Interactions by Affinity Capillary Electrophoresis (ACE) |
Hermann WÄTZIG (TECHNICAL UNIVERSITY BRAUNSCHWEIG, Braunschweig, Germany) |
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| Session chairs: |
Eric FRANCOTTE (NOVARTIS, Nuglar, Switzerland) David LLOYD (BRISTOL-MYERS SQUIBB, New Brunswick, United States) |
11:10 | Is Modern SFC a Viable Alternative to RPLC in Pharmaceutical Analysis? |
Davy GUILLARME (UNIVERSITY OF GENEVA, Geneva, Switzerland) |
11:40 | Definition of a Generic Chiral Separation Strategy on Polysaccharide-Based Chiral Stationary Phases in Supercritical Fluid Chromatography |
Debby MANGELINGS (VRIJE UNIVERSITEIT BRUSSEL, Brussels, Belgium) |
12:00 | Determination of the Enantiomeric Ratio of Drugs Using New SFC-MS/MS Instruments |
Maria Kristina PARR (FREE UNIVERSITY BERLIN, Berlin, Germany) |
12:20 | Quantitative Performances of UHPSFC AND UHPLC: A Comparative Study |
Amandine DISPAS (ULG, LIEGE, Belgium) |
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12:40 | Sandwich Lunch and Exhibition |
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13:40 | Waters Technical Seminar (30 min)
& Poster Session 1 |
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14:25 | Poster Session 1 |
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14:25 | Tutorial: Separation of Enantiomers of Chiral Drugs by Liquid-Phase Techniques
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Bezhan CHANKVETADZE (TBILISI STATE UNIVERSITY, Tbilisi, Georgia) |
15:10 | Coffee Break & Poster Session 1 |
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| Session chairs: |
Rainer BISCHOFF (UNIVERSITY OF GRONINGEN, Groningen, The Netherlands) Roman KALISZAN (MEDICAL UNIVERSITY OF GDANSK, Gdansk, Poland) |
15:30 | Pharmacometabolomics: a Tool for Drug Discovery and Personalised Medicine |
Coral BARBAS (SAN PABLO - CEU UNIVERSITY, Madrid, Spain) |
Session 3 | Session 4 |
| Session chairs: |
Rainer BISCHOFF (UNIVERSITY OF GRONINGEN, Groningen, The Netherlands) Roman KALISZAN (MEDICAL UNIVERSITY OF GDANSK, Gdansk, Poland) |
16:10 | Utility of CE-MS and HILIC-MS for Untargeted Analysis of the Anionic Urinary Metabolome |
Govert SOMSEN (VU UNIVERSITY AMSTERDAM, Amsterdam, The Netherlands) |
16:40 | Sheathless Capillary Electrophoresis-Mass Spectrometry: An Enabling Technology for Small-Volume Metabolomics Studies |
Rawi RAMAUTAR (LEIDEN UNIVERSITY, Leiden, The Netherlands) |
17:00 | NMR in the Pharmaceutical and Biomedical Areas for Identification and Quantification of Drugs and Metabolomic Applications |
Pascal DE TULLIO (ULG, Liege, Belgium) |
17:20 | In-Vitro Phenotyping for Toxicological Purposes: New Insights with the Cocktail Approach |
Serge RUDAZ (UNIVERSITY OF GENEVA, Geneva, Switzerland) |
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| Session chairs: |
Ulrike HOLZGRABE (UNIVERSITY OF WUERZBURG, Wuerzburg, Germany) |
16:10 | Analytical Needs within Innovative Manufacturing of Future Pharmaceuticals |
Jukka RANTANEN (UNIVERSITY OF COPENHAGEN, Kobenhavn, Denmark) |
16:40 | Development of a Multiplexed Surface-Enhanced Raman Scattering Quantitatve Approach for Bisphenol Detection |
Charlotte DE BLEYE (ULG, Liege, Belgium) |
17:00 | In-Line Mammalian Cells Culture Monitoring: Comparison of Predictive Performances Offered by NIR and Raman Spectroscopies |
David DIDION (UMONS, Mons, Belgium) |
17:20 | Cell Culture Monitoring by Near Infrared Spectroscopy |
Matthieu CLAVAUD (F. HOFFMANN - LA ROCHE LTD, Kaiseraugst, Switzerland) |
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18:30 | Welcome drink |
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Tuesday June 24, 2014 |
| Session chairs: |
Thomas KARNES (VIRGINIA COMMONWEALTH UNIVERSITY, Richmond, Virginia, United States) Jean-Luc VEUTHEY (UNIVERSITY OF GENEVA, Geneva, Switzerland) |
09:00 | The Nanoliter Lab: Using Droplet Microfluidics to Screen Enzymes and Protein-Protein Interactions |
Robert KENNEDY (UNIVERSITY OF MICHIGAN, Michigan, United States) |
09:40 | Break |
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Session 5 | Session 6 |
| Session chairs: |
Thomas KARNES (VIRGINIA COMMONWEALTH UNIVERSITY, Richmond, Virginia, United States) Jean-Luc VEUTHEY (UNIVERSITY OF GENEVA, Geneva, Switzerland) |
09:45 | Development of Selective Extraction Sorbents from the Macro- to the Microscale for the Trace Analysis in Complex Media |
Valerie PICHON (ESPCI, Paris, France) |
10:15 | Coffee Break |
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10:40 | In Vivo Monitoring of Neuropeptides In the Rat Hippocampus Using Nano UPLC-ESI-MS/MS |
Katrien MAES (VRIJE UNIVERSITEIT BRUSSEL, Jette, Belgium) |
11:00 | Gas Pressure Assisted Micro-Liquid-Liquid-Extraction-nanoESI-DI-MS: A New Fully-Automated Platform for Bionanalysis |
Robert-Jan RATERINK (LEIDEN UNIVERSITY, Leiden, The Netherlands) |
11:20 | Quantitation of Hepcidin in Dried Blood Spots by Microfluidic LC-CHIP/MS-MS |
Virginie HOUBART (ULG, Liège, Belgium) |
11:40 | Functionalized Polymeric Monolithic Columns in Micro-Hplc for Pharmaceutical Analysis |
Zhengjin JIANG (JINAN UNIVERSITY, Guangzhou, China) |
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| Session chairs: |
Vincenza ANDRISANO (UNIVERSITÀ DI BOLOGNA, Rimini, Italy) Uwe KARST (UNIVERSITY OF MUENSTER, Muenster, Germany) |
09:45 | Analytical Armamentarium for the Structural Characterization of Neo-Glycoproteins |
Gabriella MASSOLINI (UNIVERSITY OF PAVIA, Pavia, Italy) |
10:15 | Coffee Break |
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10:40 | Determination of Drug-Albumin Binding Modes by Induced CD Spectroscopy and TD-DFT Calculations |
Carlo BERTUCCI (UNIVERSITY OF BOLOGNA, Bologna, Italy) |
11:00 | Why Capillary Electrophoresis is an Ideal Tool for Drug Screening |
Myriam TAVERNA (UNIVERSITE PARIS SUD, Chatenay Malabry, France) |
11:20 | Immunoaffinity + LC-MS/MS: An Alternative Approach for Antibody Selectivity Evaluation? |
Trine G. HALVORSEN (UNIVERSITY OF OSLO, Oslo, Norway) |
11:40 | Hyphenated Techniques for the Bioanalytical Study of Enzymes |
Ann VAN SCHEPDAEL (KULEUVEN, Leuven, Belgium) |
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12:00 | Sandwich Lunch and Exhibition |
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13:00 | Thermo Scientific Technical Seminar (30 min)
& Poster Session 2 |
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13:45 | Poster Session 2 |
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13:45 | Tutorial: An Analysis of the New USP Validation Guidelines
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Bruno BOULANGER (ULG, Liege, Belgium) |
14:30 | Coffee Break & Poster Session 2 |
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| Session chairs: |
Carlo BERTUCCI (UNIVERSITY OF BOLOGNA, Bologna, Italy) Gerhardus J. DE JONG (UTRECHT UNIVERSITY, Utrecht, The Netherlands) |
14:50 | Spatially-Resolved Analysis of Metallopharmaceuticals by Elemental Bioimaging |
Uwe KARST (UNIVERSITY OF MUENSTER, Muenster, Germany) |
Session 7 | Session 8 |
| Session chairs: |
Carlo BERTUCCI (UNIVERSITY OF BOLOGNA, Bologna, Italy) Gerhardus J. DE JONG (UTRECHT UNIVERSITY, Utrecht, The Netherlands) |
15:30 | New Analytical Strategies for Drug Metabolism Studies |
Filip CUYCKENS (JOHNSON & JOHNSON PHARMACEUTICAL, Beerse, Belgium) |
16:00 | Mass Spectrometric Approach for the Characterization of Inhibitors of Amiloyd Aggregation Process |
Jessica FIORI (UNIVERSITY OF BOLOGNA, Bologna, Italy) |
16:20 | Development of Highly Selective LC/MS Assay for Vitamin D Metabolites |
Gwenael SCOLAN (SIGMA-ALDRICH, Poole, United Kingdom) Anders FRIDSTROM (SIGMA-ALDRICH, St Gallen , Switzerland) |
16:40 | The Medium-Throughput Determination of Hydrophobicity and Dissociation Constant by LC-MS |
Lukasz KUBIK (MEDICAL UNIVERSITY OF GDANSK, Gdansk, Poland) |
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| Session chairs: |
Bezhan CHANKVETADZE (TBILISI STATE UNIVERSITY, Tbilisi, Georgia) Ann VAN SCHEPDAEL (KULEUVEN, Leuven, Belgium) |
15:30 | Analysis of Large Biomolecules: New Strategies |
Jean-Luc VEUTHEY (UNIVERSITY OF GENEVA, Geneva, Switzerland) |
16:00 | Full Evaporation Headspace Gas Chromatography for Analysis of High Boiling Organic Compounds |
Erwin ADAMS (KULEUVEN, Leuven, Belgium) |
16:20 | Highly Enantioselective Mip-Based Porous Ultra-Thin Film in The Fabrication of an Electrochemical Sensor for the Chiral Analysis of beta-Blockers |
Ede BODOKI ("IULIU HATIEGANU" UNIVERSITY OF MEDICINE AND PHARMACY, Cluj-Napoca, Romania) |
16:40 | HPLC Chiral Separation of N-Fluorenylmetoxycarbonyl Alpha-Amino Acids Using Polysaccharide Based Chiral Stationary Phase |
Marc JACOB (PHENOMENEX, Torrance, United States) |
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17:00 | Waters Technical Seminar |
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19:30 | Banquet |
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Wednesday June 25, 2014 |
| Session chairs: |
Gabriella MASSOLINI (UNIVERSITY OF PAVIA, Pavia, Italy) Govert SOMSEN (VU UNIVERSITY AMSTERDAM, Amsterdam, The Netherlands) |
09:00 | Proteomics, Bioinformatics and Biopharmaceuticals |
Alain VAN DORSSELAER (UNIVERSITY OF STRASBOURG, Strasbourg, France) |
09:40 | Break |
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Session 9 | Session 10 |
| Session chairs: |
Gabriella MASSOLINI (UNIVERSITY OF PAVIA, Pavia, Italy) Govert SOMSEN (VU UNIVERSITY AMSTERDAM, Amsterdam, The Netherlands) |
09:45 | State of the Art Mass Spectrometry Methods for Antibodies, Biosimilars, Bispecifics and ADCs Characterization |
Alain BECK (PIERRE FABRE, St Julien-en-Genevois, France) |
10:15 | Coffee Break |
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10:40 | Capillary Electrophoresis - Mass Spectrometry for Characterization of Protein Drugs and Determination of Protein-Protein Interactions |
Gerhardus J. DE JONG (UTRECHT UNIVERSITY, Utrecht, The Netherlands) |
11:00 | In-Depth Glycan Analysis of the Biotherapeutic Enbrel (Etanercept) Using HILIC UPLC/FLR and Mass Spectrometry |
Mark HILLIARD (NATIONAL INSTITUTE FOR BIOPROCESSING RESEARCH & TRAINING, Blackrock, Ireland) |
11:20 | Study of Virus-Like Particles of Human Papillomavirus (HPV-VLP) by Capillary Electrophoresis |
Anne-Catherine SERVAIS (ULG, Liege, Belgium) |
11:40 | Expanding the Role of Capillary Electrophoresis with Mass Spectrometry Detection (CESI-MS) for the Development, Characterization & Control of Biologics |
Stephen LOCK (AB SCIEX, Warrington, United Kingdom) |
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| Session chairs: |
Philippe HUBERT (UNIVERSITY OF LIEGE, Liege, Belgium) Serge RUDAZ (UNIVERSITY OF GENEVA, Geneva, Switzerland) |
09:45 | Analytical Quality by Design |
David LLOYD (BRISTOL-MYERS SQUIBB, New Brunswick, United States) |
10:15 | Coffee Break |
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10:40 | Possibilities of Retention Modeling for HILIC and SFC Separations |
Eva TYTECA (VRIJE UNIVERSITEIT BRUSSEL, Elsene, Belgium) |
11:00 | Development of Analytical Methodology to Support a QBD Approach to Formulation Design: A Case Study |
Emma QUIRK (BRISTOL-MYERS SQUIBB, Wirral, United Kingdom) |
11:20 | Surface Acoustic Wave Biosensor as an Analytical Tool in Pharmaceutics: A Quality by Design Approach |
Nathalie BRACKE (GHENT UNIVERSITY, Ghent, Belgium) |
11:40 | Supporting Analytical Quality by Design with Informatics - A Silent Enabler |
Dan CHAPMAN (WATERS CORPORATION, Elstree, Herts, United Kingdom) |
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12:00 | Sandwich Lunch and Exhibition |
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13:00 | AB Sciex Technical Seminar (30 min) |
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Session 11 | Session 12 |
| Session chairs: |
Janusz PAWLISZYN (UNIVERSITY OF WATERLOO, Waterloo Ontario, Canada) Quezia CASS (FEDERAL UNIVERSITY OF SÃO CARLOS, São Carlos, Brazil) |
13:45 | Analytical Microextraction Across Supported Liquid Membranes - Principles, Applications and Recent Developments |
Stig PEDERSEN BJERGAARD (UNIVERSITY OF OSLO, Oslo, Norway) |
14:15 | Preparation of Molecularly Imprinted Polymers for Hydrophilic Compounds by Modified Precipitation Polymerization |
Jun HAGINAKA (MUKOGAWA WOMEN'S UNIVERSITY, Hyogo, Japan) |
14:35 | Validation of the Analytical Procedure for the Determination of the Underivatized Neurotoxin Beta-N-Methylamino-L-Alanine by LC/MS-MS in Environmental Samples and in Human Brain |
Audrey COMBES (ESPCI, Paris, France) |
14:55 | Parallel Artificial Liquid Membrane Extraction (Palme) – An Innovative Implementation of Supported Liquid Membrane Extractions into a Multiwell Plate |
Astrid GJELSTAD (UNIVERSITY OF OSLO, Oslo, Norway) |
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| Session chairs: |
Joëlle QUETIN-LECLERCQ (UNIVERSITÉ CATHOLIQUE DE LOUVAIN (UCL), Brussels, Belgium) Rawi RAMAUTAR (LEIDEN UNIVERSITY, Leiden, The Netherlands) |
13:45 | Quality Control of Chinese Herbal Medicines |
Rudolf BAUER (UNIVERSITY OF GRAZ, Graz, Austria) |
14:15 | Residual Solvents: A Potential Threat Present In Counterfeit Medicines |
Eric DECONINCK (WIV-ISP, Brussel, Belgium) |
14:35 | LC-SPE-NMR Identification and NMR Quantification of Salvia Fruticosa Phytochemicals with Antifungal Activity |
Vasiliki EXARCHOU (UNIVERSITY OF ANTWERP, Antwerp, Belgium) |
14:55 | Synthesis and Degradation Impurities in Peptide Drugs |
Matthias D'HONDT (UGENT, Gent, Belgium) |
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15:15 | Break |
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| Session chair: |
Stig PEDERSEN BJERGAARD (UNIVERSITY OF OSLO, Oslo, Norway) |
15:20 | SPME-LC-MS for Drug Bioanalysis, a New Tool for in vivo Sampling and High Throughput Determinations |
Janusz PAWLISZYN (UNIVERSITY OF WATERLOO, Waterloo Ontario, Canada) |
16:00 | Closing remarks |
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