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| Sunday April 23, 2017 |
| 17:00 | Registration |
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| 18:00 | Dinner |
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| Monday April 24, 2017 |
| 07:30 | Breakfast |
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| 08:30 | Introduction
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| 09:00 | Mathematics of binding kinetics
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Prof. Georges VAUQUELIN
(VUB, Brussel, Belgium) |
| 10:30 | Coffee Break |
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| 11:00 | Mathematics of binding kinetics - Part II |
Prof. Georges VAUQUELIN
(VUB, Brussel, Belgium) |
| 12:30 | Lunch |
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| 13:30 | Characterizing the Dynamics of Molecular Interactions |
Prof. Helena DANIELSON
(UPPSALA UNIVERSITY, Uppsala, Sweden) |
| 15:00 | Coffee Break |
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| 15:30 | Characterizing the Dynamics of Molecular Interactions - Part II |
Prof. Helena DANIELSON
(UPPSALA UNIVERSITY, Uppsala, Sweden) |
| 17:00 | Day End |
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| 18:00 | Dinner and walking tour through Leiden |
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| Tuesday April 25, 2017 |
| 07:30 | Breakfast |
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| 08:30 | Kinetics for drug discovery: In vitro assays to study GPCRs |
Dr Laura HEITMAN
(UNIVERSITY OF LEIDEN, Leiden, The Netherlands) |
| 10:00 | Coffee Break |
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| 10:30 | Kinetics in Drug Discovery - A Case for G Protein-coupled Receptors |
Prof. Ad P. IJZERMAN
(UNIVERSITY OF LEIDEN, Leiden, The Netherlands) |
| 12:00 | Lunch |
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| 13:00 | Pharmacokinetic-pharmacodynamic Relationships, the Connecting Role of Binding Kinetics |
Dr Liesbeth DE LANGE (UNIVERSITY OF LEIDEN, Leiden, The Netherlands)
Mr Wilbert DE WITTE (UNIVERSITY OF LEIDEN, Leiden, The Netherlands) |
| 15:00 | Coffee Break |
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| 15:30 | Pharmacokinetic-pharmacodynamic Relationships, the Connecting Role of Binding Kinetics - Part II |
Mr Wilbert DE WITTE (UNIVERSITY OF LEIDEN, Leiden, The Netherlands)
Dr Liesbeth DE LANGE (UNIVERSITY OF LEIDEN, Leiden, The Netherlands) |
| 17:00 | Day End |
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| 18:00 | Dinner |
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| Wednesday April 26, 2017 |
| 07:30 | Breakfast |
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| 08:30 | The Use of Kinetic Data in Early Drug Discovery: HSP90 as a Model to Gain Mechanistic Insight into Drug Binding Kinetics |
Dr Matthias FRECH
(MERCK, Darmstadt, Germany) |
| 10:00 | Coffee Break |
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| 10:30 | The Use of Kinetic Data in Early Drug Discovery: HSP90 as a Model to Gain Mechanistic Insight into Drug Binding Kinetics - Part II |
Dr Matthias FRECH
(MERCK, Darmstadt, Germany) |
| 12:00 | Wrap-up and Lunch |
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