Keynote Lecture
The Fascinating World of Medicinal Chemistry and Drug Discovery
 | Dr Christoph BOSS (IDORSIA PHARMACEUTICALS LTD, Allschwil, Switzerland) Read more
Christoph Boss studied chemistry at the University of Bern / Switzerland from 1988 to 1996 and finished his studies in 1996 with a Ph D in synthetic organic chemistry under the supervision of Prof Reinhart Keese. He spent a postdoctoral year at The Scripps Research Institute in LaJolla in the group of Prof. Julius Rebek and afterwards returned to Switzerland to start working in a Process Research group in a Speciality and Custom Chemicals Company (CABB) for one year. Then he moved to Actelion Pharmaceuticals Ltd in early 1999 to start working as a lab head in medicinal chemistry. He was promoted to group leader in 2002 and to Director Medicinal Chemistry and Senior Group Leader in 2004 and to Senior Director Medicinal Chemistry, Senior Group Leader in 2006. His research interests are manifold and he contributed to the identification of the endothelin antagonist Macitentan (marketed as Opsumit®), to several renin inhibitors entering clinical trials as well as to three orexin receptor antagonists of which the most advanced is in phase II clinical development at the moment. Since 2013 he is Senior Director, Senior Group Leader of the "Chemistry Technology and Lead Discovery" Team, responsible for early projects chemistry support, hit-to-lead projects, the screening compound collection, all aspects of computational chemistry, the high throughput medicinal chemistry team, and the analytics and purification team. Dr. Boss is a co-inventor on 100 published patent applications and a co-author on more than 55 papers, abstracts, book chapters, commentaries, editorials and reviews. Close window
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Challenging Medicinal Chemistry!
 | Dr Peter NUSSBAUMER (LEAD DISCOVERY CENTER, Dortmund, Germany) Read more
Dr. Peter Nussbaumer has more than 30 years of industry experience in drug discovery and early drug development. Currently, he is Managing Director and Head of Medicinal Chemistry at the Lead Discovery Center GmbH (LDC) in Dortmund, Germany. In this function Peter has been co-responsible for building-up and running this unique translational drug discovery organisation founded by the Max Planck Society, working at the interface of academia and industry. He is member of several international scientific advisory boards and serves as advisor to private and public funding bodies. Peter is (co)author of >25 patent applications and >70 peer-reviewed publications and referee to various journals.
Before joining LDC, Peter was Executive Director at the Novartis Institutes for BioMedical Research in Vienna, Austria, heading the Chemistry Department. Peter has a Dr. degree from the Vienna University of Technology, Austria. Close window
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Oral Communications
OC01 - A Novel Hydantoin-Based Series of Dpre1 Inhibitors in M.Tuberculosis: Hit-to-Lead Optimization and Biological Profiling
| Ms Olga BALABON (UNIVERSITY OF ANTWERP, Wilrijk, Belgium) |
OC07 - Design and Synthesis of Functionalized Monocyclic 3-Amino-1-Carboxymethyl-Beta-Lactams as Potential Inhibitors of Penicillin Binding Proteins of Resistant Bacteria
| Ms Lena DECUYPER (GHENT UNIVERSITY, Gent, Belgium) |
OC18 - Molecular Recognition and Activation Mechanisms of Bitter Taste Receptors
Winner of the young medicinal chemist meeting in Israel
| Dr Antonella DI PIZIO (THE HEBREW UNIVERSITY OF JERUSALEM, Rehovot, Israel) |
OC17 - Modular Assembly of Reversible Multivalent Targeting Drug Conjugates
Winner of the young medicinal chemist meeting in Portugal
| Mr Fábio Miguel FIGUEIREDO SANTOS (RESEARCH INSTITUTE FOR MEDICINES (IMED.ULISBOA), Lisboa, Portugal) |
OC02 - Target Elucidation of Novel Trypanosomatid Inhibitors
Winner of the young medicinal chemist meeting in the United Kingdom
| Mr Andrew FRASER (UNIVERSITY OF ST ANDREWS, Ayr, United Kingdom) |
OC16 - The Catalytic Mechanism of The Iron-dependent Sulfoxide Synthase EgtB
Winner of the young medicinal chemist meeting in Switzerland
| Dr Kristina GONCHARENKO (UNIVERSITY OF BASEL, Basel, Switzerland) |
OC09 - Bicyclic Constrained Peptides Targeting the EGF-EGFR Interaction
Winner of the young medicinal chemist meeting in Spain
| Mr Salvador GUARDIOLA (INSTITUTE FOR RESEARCH IN BIOMEDICINE, Barcelona, Spain) |
OC05 - Identification of potent inhibitors of the anti-infective target DXS using ligand-based virtual screening
Winner of the young medicinal chemist meeting in Germany (DPhG)
| Prof. Anna K. H. HIRSCH (HELMHOLTZ INSTITUTE FOR PHARMACEUTICAL RESEARCH SAARLAND, Saarbrücken, Germany) |
OC12 - Development of Ligands for the Short-Chain Fatty Acid Receptor Ffa2
Winner of the young medicinal chemist meeting in Denmark
| Mr Anders HOJGAARD HANSEN (UNIVERSITY OF SOUTHERN DENMARK, Odense M, Denmark) |
OC04 - Development of Non-Covalent In Vivo Active Butyrylcholinesterase Inhibitors
Winner of the young medicinal chemist meeting in Slovenia
| Mr Urban KOSAK (UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia) |
OC03 - Design, Synthesis and Biological Evaluation of New Artemisinin Hybrid Molecules
Winner of the young medicinal chemist meeting in Greece
| Mr Antonios S. LETIS (UNIVERSITY OF PATRAS, Patras, Greece) |
OC11 - Facing Non-Alcoholic Steatohepatitis with Multitarget Compounds
| Dr Daniel MERK (ETH ZÜRICH, Zürich, Switzerland) |
OC14 - Building-up Molecular Complexity with Carbenoids: New Vistas in Homologation Chemistry
Winner of the young medicinal chemist meeting in Austria
| Dr Vittorio PACE (UNIVERSITY OF VIENNA, Vienna, Austria) |
OC13 - Fluorophore One-Atom-Controlled Recognition of DNA/RNA Secondary Structure
Winner of the young medicinal chemist meeting in Croatia
| Ms Tamara SMIDLEHNER (RUDER BOSKOVIC INSTITUTE, Zagreb, Croatia) |
OC10 - Discovery and Characterization of Novel Potent F508-Del Cftr Correctors
| Dr Federico SORANA (FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA, GENOVA, Italy) |
OC15 - The Role of The Sulfonyl Group on The Conformational Preferences Of Bis-Aromatic Compounds ¬ 5-Ht6 Receptor Antagonists and Beyond
Winner of the young medicinal chemist meeting in Poland
| Dr Jakub STARON (INSTITUTE OF PHARMACOLOGY PAS, Krakow, Poland) |
OC08 - Discovery and Optimization of Novel Inhibitors for the Ether Lipid-Generating Enzyme AGPS as Anticancer Agents
Winner of the young medicinal chemist meeting in Italy
| Dr Sergio VALENTE (SAPIENZA UNIVERSITY OF ROME, Rome, Italy) |
OC06 - In Situ Ugi Four-Component Reaction for the Protein-Templated Identification of Inhibitors of Endothiapepsin
Winner of the young medicinal chemist meeting in the Netherlands
| Mr M. Yagiz ÜNVER (UNIVERSITY OF GRONINGEN, Groningen, The Netherlands) |