SAR By XRay: A New Approach Combining Screening and Rational Drug Design. Application to the Discovery of Nanomolar Src SH2 Binders
Dr Dominique LESUISSE (SANOFI AVENTIS, Chilly-Mazarin, France)
15:00
Molecular Design, Chemical Synthesis and Biological Evaluation of Quinoxaline-Carbohydrate Hybrids as Novel and Selective Photo-Induced Dna Cleaving and Cytotoxic Agents
Prof. Kazunobu TOSHIMA (KEIO UNIVERSITY, YOKOHAMA, Japan)
15:10
Coffee break
15:40
From Synthetic Polyelectrolites to Vaccinating Macromolecules
Prof. Viktor A. KABANOV (RUSSIAN ACADEMY OF SCIENCES, Russia)
16:30
Arene-Arene Interactions Between the Substrate and the Organocatalyst as the Driving Force In the Asymmetric Allylation of Aldehydes with Allyltrichlorosilanes.
Dr Andrei MALKOV (UNIVERSITY OF GLASGOW, Glasgow, United Kingdom)
16:40
Asymmetric Approach to Proline-Derived Spiro-Β-Lactams - Staudinger Reaction of N-Protected-4-Methanesulfonyloxy-L-Proline with N-Aryl Imines
Dr Mohan THIRUVAZHI (CHEMBRIDGE RESEARCH LABORATORIES, SAN DIEGO, United States)
16:50
Hit and Lead Generation - Beyond High Throughput Screening
Dr Alexander ALANINE (INDEPENDANT RESEARCHER, Brinckheim, France)
19:00
Optional: Swan Lake Ballet at
the Bolshoï Theater
21:30
Moscow by night guided tour (First
departure)
22:00
Moscow by night guided tour (Second
departure)
07/05/2004
08:30
Synthesis and Pharmacological Characterization of Novel Epothilone Derivatives
Dr Rainer METTERNICH (CAPROTEC BIOANALYTICS, Basel, Switzerland)
09:05
The Discovery of BIBN4096, a Novel CGRP Antagonist for the Treatment of
Migraine
Prof. Dr. Gerd SCHNORRENBERG (BOEHRINGER INGELHEIM PHARMA KG, Biberach an der Riss, Germany)
09:30
The Synthesis of Biarylthioether derivatives as GlyT1 Inhibitors
Dr Garrick SMITH (H. LUNDBECK A/S, VALBY, Denmark)
09:55
Catalytic Synthesis of Azoles, or Teaching an Old Dog New Tricks
Prof. Valery FOKIN (THE SCRIPPS RESEARCH INSTITUTE, LA JOLLA, United States)
