Drug Analysis 2010
20/09/2010
16:00Registration (until 18:00) in Aula Rector Dhanis
21/09/2010
(Aula Rector Dhanis)
08:00Registration
09:00Opening Ceremony
BSPS Prize Ceremony
Sandra APERS (UNIVERSITY OF ANTWERP, Antwerp, Belgium)
Jacques CROMMEN (UNIVERSITY OF LIEGE, Liege, Belgium)
09:30Metabolomics: Opportunities for Personalized Health
Thomas HANKEMEIER
(NETHERLANDS METABOLOMICS CENTER, Leiden, The Netherlands)
10:10Metabonomics-driven Top-down Systems Biology: Techniques and Applications
John C. LINDON
(IMPERIAL COLLEGE, London, United Kingdom)
10:50Coffee Break and Exhibition
Parallel Session A: Session 1Parallel Session B: Session 2
(Aula R - Room R001)
11:10Searching for Biomarkers in Abdominal Aneurysm through a Metabolomic Approach
Coral BARBAS
(SAN PABLO - CEU UNIVERSITY, Madrid, Spain)
11:40Efficient and Comprehensive Metabolic Profiling by CE-TOF-MS
Gerhardus J. DE JONG
(UNIVERSITY OF UTRECHT, Utrecht, The Netherlands)
12:00Metabonomic Platform for Modified Nucleoside Analyses in Urine of Urogenital Cancerous Patients as a New Prognostic Tool in Bioanalysis
Michal MARKUSZEWSKI
(MEDICAL UNIVERSITY OF GDANSK, Gdansk, Poland)
12:20Quantitative and Qualitative Analysis of Biologically Active Saponins of M. lanceolata
Kenn FOUBERT
(UNIVERSITY OF ANTWERP, Wilrijk, Belgium)
(Aula R - Room R002)
11:10The key role of Process Analytical Technology in Quality by Design driven drug discovery and development
Staffan FOLESTAD
(ASTRAZENECA, Molndal, Sweden)
11:40Evaluation of Flashsizer 3d Imaging during an Extrusion-spheronization Process
Anneleen BURGGRAEVE
(GHENT UNIVERSITY, Ghent, Belgium)
12:00In-process Control of Solubilized Hard Gelatin Capsule Formulations Using ATR-UV and Lasentec Light Scattering
Xujin LU
(BRISTOL-MYERS SQUIBB, NEW BRUNSWICK, United States)
12:20NIR and Raman Spectroscopy as PAT Tools for the Manufacturing of Silicone-based Drug Reservoirs
Jérôme MANTANUS
(ULG, Liège, Belgium)
12:40Lunch & Exhibition
13:45Poster Session (Group 1)
15:00Coffee break served in poster area
Parallel Session A: Session 3Parallel Session B: Session 4
(Aula R - Room R001)
15:30LC-SPE-NMR as a Tool for the Profiling of Herbal Medicinal Products
Luc PIETERS
(UNIVERSITY OF ANTWERP, Antwerp, Belgium)
16:00A Validated Method Combining SPE and HPLC-UV for the Quantification of Rotenone in Seeds of Yam Bean (Pachyrhizus sp.)
Emmanuelle LAUTIÉ
(UCL, Bruxelles, Belgium)
16:20Headspace-solid-phase Microextraction Gas Chromatography-mass Spectrometry (HS-SPME-GC-MS) Determination of Odorants in Green Tea
Jessica FIORI
(UNIVERSITY OF BOLOGNA, Bologna, Italy)
16:40Application of Experimental Design and Design for the Separation of Compounds Extracted from the Leaves of Strychnos Usambarensis
Iolanda NISTOR
(UNIVERSITY OF LIÈGE, Liège, Belgium)
(Aula R - Room R002)
15:30The Use of LC-MS(MS) in Doping Control Analysis
Koen DEVENTER
(UNIVERSITY OF GHENT (DOCOLAB), Zwijnaarde, Belgium)
16:00LC-MS Metabonomic Approach Leading Tohuman Urinary Signatures of Different Drugs
Agneta KISS
(CNRS, Solaize, France)
16:20Batch Analysis of Internet-sourced Mephedrone
Nagendra SINGH
(UNIVERSITY OF SUNDERLAND, Sunderland, United Kingdom)
16:40Designer Steroid 3β-hydroxy-5α-androst-1-ene-17-one: Identification in a Seized Dietary Supplement and its Urinary Metabolism
Maria Kristina PARR
(GERMAN SPORT UNIVERSITY COLOGNE, Cologne, Germany)
17:00 Waters Workshop
19:00Cocktail offered by the city of Antwerp
22/09/2010
(Aula Rector Dhanis)
09:00The Enantioselective Pharmacokinetics and Pharmacodynamics of (R,S)-ketamine in the Treatment of Complex Regional Pain Syndrome: A Reexamination of an Old Drug
Irving W. WAINER
(NATIONAL INSTITUTE ON AGING, Baltimore, United States)
Parallel Session A: Session 5Parallel Session B: Session 6
(Aula R - Room R001)
09:45Cyclodextrin-based Chiral Separations by Capillary Electrophoresis in J. Crommen’s lab : a Twenty Years Story
Marianne FILLET
(UNIVERSITY OF LIEGE, Liege, Belgium)
(Aula R - Room R002)
09:45Analytical Strategies for the Characterization of Protein Aggregation and its Inhibition in Human Diseases
Vincenza ANDRISANO
(UNIVERSITÀ DI BOLOGNA, Rimini, Italy)
10:15Coffee Break and exhibition
Parallel Session A: Session 5Parallel Session B: Session 6
11:00Separation Mechanism of some Chiral Drugs in Capillary Electrophoresis
Bezhan CHANKVETADZE
(TBILISI STATE UNIVERSITY, Tbilisi, Georgia)
11:20olysaccharide-Type Chiral Selectors: The Impact of Chlorine-Containing Groups on Enantioselectivity in Polar Organic Solvent Chromatography
Hasret ATES
(VUB, Brussels, Belgium)
11:40Amino Acids Chiral Separation by Capillary Electrophoresis with In-Capillary Sample Preconcentration and Chemical Derivatisation
Ines FRADI
(LABORATOIRE NATIONAL DE CONTRÔLE DES MÉDICAMENTS, TUNISIE, Liège, Belgium)
11:00Screening of potential ligands using an immobilized enzyme reactor based on purine nucleoside phosphorylase from S. mansoni
Quezia CASS
(FEDERAL UNIVERSITY OF SÃO CARLOS, São Carlos, Brazil)
11:20Frontal Analysis Coupled to Mass Spectrometry for Ligand-binding Affinity Studies
Gabriella MASSOLINI
(UNIVERSITY OF PAVIA, Pavia, Italy)
11:40In-capillary Screening of Matrix Metalloproteinase Inhibitors by Electrophoretically Mediated Microanalysis with Fluorescence Detection
Xin HAI
(KULEUVEN, Leuven, Belgium)
12:00Lunch and Exhibition
14:00Excursion
23/09/2010
(Aula Rector Dhanis)
09:00UHPLC : a Fast and Efficient Tool in Pharmaceutical Analysis
Jean-Luc VEUTHEY
(UNIVERSITY OF GENEVA, Geneva, Switzerland)
09:40Break
Parallel Session A: Session 7Parallel Session B: Session 8
(Aula R - Room R001)
09:45Analysis Strategies to Uncover and Avoid Counterfeit Drugs
Ulrike HOLZGRABE
(UNIVERSITY OF WUERZBURG, Wuerzburg, Germany)
10:15Easy Update of LC Methods for Purity Control of Antibiotics
Erwin ADAMS
(KULEUVEN, Leuven, Belgium)
(Aula R - Room R002)
09:45Nanobiodevice Based Single Cell Analysis for Cancer Diagnosis and in Vivo Imaging for Stem Cell Therapy
Yoshinobu BABA
(NAGOYA UNIVERSITY, Nagoya, Japan)
10:15Towards characterization of pharmaceutical proteins by capillary electrophoresis combined with mass and fluorescence spectrometry
Govert SOMSEN
(VU UNIVERSITY AMSTERDAM, Amsterdam, The Netherlands)
10:45Coffee Break
Parallel Session A: Session 7Parallel Session B: Session 8
11:05Contribution of Near Infrared Spectroscopy for Counterfeit Pharmaceutical Detection: Feasibility Study and Application to Examples
HERVE REBIERE
(AFSSAPS, VENDARGUES, France)
11:25Desorption Atmospheric Pressure Photoionization in Routine Analysis of Confiscated Drug Samples
Tina KAUPPILA
(UNIVERSITY OF HELSINKI, Helsinki, Finland)
11:45Selective Analysis of Pharmaceuticals in Environmental Water Samples Using Restricted Access Media-Molecularly Imprinted Polymer
Jun HAGINAKA
(MUKOGAWA WOMEN'S UNIVERSITY, Hyogo, Japan)
12:05Occurrence of Veterinary Pharmaceuticals in the Aquatic Environment in Flanders
KELLY SERVAES
(VITO NV, MOL, Belgium)
11:05A Microfluidic Capillary System for Immunoaffinity and Molecular Imprinted Polymer Separations applied to Bioanalysis
Thomas KARNES
(VIRGINIA COMMONWEALTH UNIVERSITY, Richmond, Virginia, United States)
11:25High Performance Microscale Electrophoresis of Biogenic Compounds Using On-Line Sample Concentration Techniques
Koji OTSUKA
(KYOTO UNIVERSITY, Kyoto, Japan)
11:45Cytotoxicity Tests with 5-fluorouracil in a Microanalytical System
Elzbieta JEDRYCH
(WARSAW UNIVERSITY OF TECHNOLOGY, Warsaw, Poland)
12:05Nano Liquid Chromatography Tandem Mass Spectrometry for the Monitoring of Hippocampal Neuropeptides Possibly Involved in Limbic Epilepsy
Ann VAN EECKHAUT
(FREE UNIVERSITY OF BRUSSELS (VUB), Brussels, Belgium)
12:25Lunch & Exhibition
12:45Thermo Fisher Scientific Workshop
13:30Poster Session (Group 2)
Parallel Session A: Session 9Parallel Session B: Session 10
(Aula R - Room R001)
15:30Total Error as Natural Decision Criteria for Analytical Methods Validation and Transfer
Eric ROZET
(UNIVERSITY OF LIEGE, Liege, Belgium)
16:00Simultaneous Quantification of 10 Cytotoxic Drugs by a Validated LC-ESI-MS/MS Method
Susanne NUSSBAUMER
(HÔPITAUX UNIVERSITAIRE DE GENÈVE HUG - PHARMACY, Geneva 14, Switzerland)
16:20Frictional Heating Effects on Scaling of HPLC/VHPLC Methods
David LLOYD
(BRISTOL-MYERS SQUIBB, New Brunswick, United States)
16:40The Role of Degradant Profiling in Active Pharmaceutical Ingredients and Drug Products
Sara VRIELYNCK
(JOHNSON & JOHNSON, Beerse, Belgium)
(Aula R - Room R002)
15:30MALDI Imaging for Small Molecules and Clinical Proteomics: Developments and Applications
Jonathan STAUBER
(IMABIOTECH, Villeneuve d’Ascq, France)
16:00Micropillar Array Electrospray Ionization Microchip – What is it good for?
Raimo KETOLA
(UNIVERSITY OF HELSINKI, Helsinki, Finland)
16:20Improving MS identification of Bacillus subtilis ΔprpE and 168 proteins with the use of QSRR-based peptides retention times prediction in RP-HPLC
Katarzyna MACUR
(MEDICAL UNIVERSITY OF GDANSK, Gdansk, Poland)
16:40Optimization of Big Protein Sequence Recovery by LC-QTOF for the Future Study of its Posttranslational Modifications.
Cédric DELPORTE
(UNIVERSITÉ LIBRE DE BRUXELLES, Bruxelles, Belgium)
19:30Banquet in "Art Nouveau Zaal" Horta
24/09/2010
(Aula Rector Dhanis)
09:00Application of Solid Phase Microextraction to Drug Development and Biomarker Discovery
Janusz PAWLISZYN
(UNIVERSITY OF WATERLOO, Waterloo Ontario, Canada)
09:40Break
Parallel Session A: Session 11Parallel Session B: Session 12
(Aula R - Room R001)
09:45Aptamer-based Sorbents as an Alternative to Immunosorbents and Molecularly Imprinted Polymers for Selective Extraction of Drugs from Biological Samples
Valerie PICHON
(ESPCI, Paris, France)
10:15Coffee Break and exhibition
11:30Evaluation of an in-capillary Approach to Perform Quantitative CYP450 Activity Studies
Juan BRAVO
(UNIVERSITY OF GENEVA, Geneva, Switzerland)
11:50Tyrosinase immobilized magnetic nanobeads for the Amperometric Assay of Enzyme Inhibitors: Application to the Skin Whitening Agents
Veronica SIMA HARCEAGA
(IULIU HATIEGANU UNIVERSITY, Cluj-Napoca, Romania)
12:10A Direct-Injection Mekc Method For Drug Analysis in the Presence of Matrix Proteins
Hermann WÄTZIG
(TECHNICAL UNIVERSITY BRAUNSCHWEIG, Braunschweig, Germany)
(Aula R - Room R002)
09:45Proteomics in Drug Analysis
Peter VERHAERT
(DELFT UNIVERSITY OF TECHNOLOGY, Delft, The Netherlands)
10:15Coffee Break and exhibition
11:30Camptothecin and Thio-camptothecin: the Role of Sulfur in Shifting the Hydrolysis Equilibrium Towards the Closed Lactone form
Carlo BERTUCCI
(UNIVERSITY OF BOLOGNA, Bologna, Italy)
11:50Polymeric Monolithic Ion-exchange Stationary Phases in Combination with pH Gradient for the Separation and Purity Profiling of Monoclonal Antibodies
Mohammad TALEBI
(UNIVERSITY OF TASMANIA, Hobart, Australia)
12:10Functional Quality of Peptides in Pharmaceutical R&D
Sylvia VAN DORPE
(GHENT UNIVERSITY, Gent, Belgium)
12:30Lunch and Exhibition
13:30Proteomic Biomarker Discovery: From Hypervariable Data to Biomarker Candidates
Rainer BISCHOFF
(UNIVERSITY OF GRONINGEN, Groningen, The Netherlands)
14:10Peptide and Oligonucleotides Aptamers as New Ligands for Analytical Chemistry
Marco MASCINI
(UNIVERSITÀ DEGLI STUDI DI FIRENZE, Sesto Fiorentino, Italy)
14:45Closing Remarks
15:00Announcements
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