Drug Analysis 2010 20/09/2010
16:00 Registration (until 18:00) in Aula Rector Dhanis
21/09/2010
(Aula Rector Dhanis)
08:00 Registration
09:00 Opening Ceremony
BSPS Prize Ceremony
Sandra APERS (UNIVERSITY OF ANTWERP, Antwerp, Belgium) Jacques CROMMEN (UNIVERSITY OF LIEGE, Liege, Belgium)
09:30 Metabolomics: Opportunities for Personalized Health
Thomas HANKEMEIER (NETHERLANDS METABOLOMICS CENTER, Leiden, The Netherlands)
10:10 Metabonomics-driven Top-down Systems Biology: Techniques and Applications
John C. LINDON (IMPERIAL COLLEGE, London, United Kingdom)
10:50 Coffee Break and Exhibition
Parallel Session A: Session 1 Parallel Session B: Session 2
(Aula R - Room R001)
11:10 Searching for Biomarkers in Abdominal Aneurysm through a Metabolomic Approach
Coral BARBAS (SAN PABLO - CEU UNIVERSITY, Madrid, Spain)
11:40 Efficient and Comprehensive Metabolic Profiling by CE-TOF-MS
Gerhardus J. DE JONG (UNIVERSITY OF UTRECHT, Utrecht, The Netherlands)
12:00 Metabonomic Platform for Modified Nucleoside Analyses in Urine of Urogenital Cancerous Patients as a New Prognostic Tool in Bioanalysis
Michal MARKUSZEWSKI (MEDICAL UNIVERSITY OF GDANSK, Gdansk, Poland)
12:20 Quantitative and Qualitative Analysis of Biologically Active Saponins of M. lanceolata
Kenn FOUBERT (UNIVERSITY OF ANTWERP, Wilrijk, Belgium)
(Aula R - Room R002)
11:10 The key role of Process Analytical Technology in Quality by Design driven drug discovery and development
Staffan FOLESTAD (ASTRAZENECA, Molndal, Sweden)
11:40 Evaluation of Flashsizer 3d Imaging during an Extrusion-spheronization Process
Anneleen BURGGRAEVE (GHENT UNIVERSITY, Ghent, Belgium)
12:00 In-process Control of Solubilized Hard Gelatin Capsule Formulations Using ATR-UV and Lasentec Light Scattering
Xujin LU (BRISTOL-MYERS SQUIBB, NEW BRUNSWICK, United States)
12:20 NIR and Raman Spectroscopy as PAT Tools for the Manufacturing of Silicone-based Drug Reservoirs
Jérôme MANTANUS (ULG, Liège, Belgium)
12:40 Lunch & Exhibition
13:45 Poster Session (Group 1)
15:00 Coffee break served in poster area
Parallel Session A: Session 3 Parallel Session B: Session 4
(Aula R - Room R001)
15:30 LC-SPE-NMR as a Tool for the Profiling of Herbal Medicinal Products
Luc PIETERS (UNIVERSITY OF ANTWERP, Antwerp, Belgium)
16:00 A Validated Method Combining SPE and HPLC-UV for the Quantification of Rotenone in Seeds of Yam Bean (Pachyrhizus sp.)
Emmanuelle LAUTIÉ (UCL, Bruxelles, Belgium)
16:20 Headspace-solid-phase Microextraction Gas Chromatography-mass Spectrometry (HS-SPME-GC-MS) Determination of Odorants in Green Tea
Jessica FIORI (UNIVERSITY OF BOLOGNA, Bologna, Italy)
16:40 Application of Experimental Design and Design for the Separation of Compounds Extracted from the Leaves of Strychnos Usambarensis
Iolanda NISTOR (UNIVERSITY OF LIÈGE, Liège, Belgium)
(Aula R - Room R002)
15:30 The Use of LC-MS(MS) in Doping Control Analysis
Koen DEVENTER (UNIVERSITY OF GHENT (DOCOLAB), Zwijnaarde, Belgium)
16:00 LC-MS Metabonomic Approach Leading Tohuman Urinary Signatures of Different Drugs
Agneta KISS (CNRS, Solaize, France)
16:20 Batch Analysis of Internet-sourced Mephedrone
Nagendra SINGH (UNIVERSITY OF SUNDERLAND, Sunderland, United Kingdom)
16:40 Designer Steroid 3β-hydroxy-5α-androst-1-ene-17-one: Identification in a Seized Dietary Supplement and its Urinary Metabolism
Maria Kristina PARR (GERMAN SPORT UNIVERSITY COLOGNE, Cologne, Germany)
17:00
Waters Workshop
19:00 Cocktail offered by the city of Antwerp
22/09/2010
(Aula Rector Dhanis)
09:00 The Enantioselective Pharmacokinetics and Pharmacodynamics of (R,S)-ketamine in the Treatment of Complex Regional Pain Syndrome: A Reexamination of an Old Drug
Irving W. WAINER (NATIONAL INSTITUTE ON AGING, Baltimore, United States)
Parallel Session A: Session 5 Parallel Session B: Session 6
(Aula R - Room R001)
09:45 Cyclodextrin-based Chiral Separations by Capillary Electrophoresis in J. Crommen’s lab : a Twenty Years Story
Marianne FILLET (UNIVERSITY OF LIEGE, Liege, Belgium)
(Aula R - Room R002)
09:45 Analytical Strategies for the Characterization of Protein Aggregation and its Inhibition in Human Diseases
Vincenza ANDRISANO (UNIVERSITÀ DI BOLOGNA, Rimini, Italy)
10:15 Coffee Break and exhibition
Parallel Session A: Session 5 Parallel Session B: Session 6
11:00 Separation Mechanism of some Chiral Drugs in Capillary Electrophoresis
Bezhan CHANKVETADZE (TBILISI STATE UNIVERSITY, Tbilisi, Georgia)
11:20 olysaccharide-Type Chiral Selectors: The Impact of Chlorine-Containing Groups on Enantioselectivity in Polar Organic Solvent Chromatography
Hasret ATES (VUB, Brussels, Belgium)
11:40 Amino Acids Chiral Separation by Capillary Electrophoresis with In-Capillary Sample Preconcentration and Chemical Derivatisation
Ines FRADI (LABORATOIRE NATIONAL DE CONTRÔLE DES MÉDICAMENTS, TUNISIE, Liège, Belgium)
11:00 Screening of potential ligands using an immobilized enzyme reactor based on purine nucleoside phosphorylase from S. mansoni
Quezia CASS (FEDERAL UNIVERSITY OF SÃO CARLOS, São Carlos, Brazil)
11:20 Frontal Analysis Coupled to Mass Spectrometry for Ligand-binding Affinity Studies
Gabriella MASSOLINI (UNIVERSITY OF PAVIA, Pavia, Italy)
11:40 In-capillary Screening of Matrix Metalloproteinase Inhibitors by Electrophoretically Mediated Microanalysis with Fluorescence Detection
Xin HAI (KULEUVEN, Leuven, Belgium)
12:00 Lunch and Exhibition
14:00 Excursion
23/09/2010
(Aula Rector Dhanis)
09:00 UHPLC : a Fast and Efficient Tool in Pharmaceutical Analysis
Jean-Luc VEUTHEY (UNIVERSITY OF GENEVA, Geneva, Switzerland)
09:40 Break
Parallel Session A: Session 7 Parallel Session B: Session 8
(Aula R - Room R001)
09:45 Analysis Strategies to Uncover and Avoid Counterfeit Drugs
Ulrike HOLZGRABE (UNIVERSITY OF WUERZBURG, Wuerzburg, Germany)
10:15 Easy Update of LC Methods for Purity Control of Antibiotics
Erwin ADAMS (KULEUVEN, Leuven, Belgium)
(Aula R - Room R002)
09:45 Nanobiodevice Based Single Cell Analysis for Cancer Diagnosis and in Vivo Imaging for Stem Cell Therapy
Yoshinobu BABA (NAGOYA UNIVERSITY, Nagoya, Japan)
10:15 Towards characterization of pharmaceutical proteins by capillary electrophoresis combined with mass and fluorescence spectrometry
Govert SOMSEN (VU UNIVERSITY AMSTERDAM, Amsterdam, The Netherlands)
10:45 Coffee Break
Parallel Session A: Session 7 Parallel Session B: Session 8
11:05 Contribution of Near Infrared Spectroscopy for Counterfeit Pharmaceutical Detection: Feasibility Study and Application to Examples
HERVE REBIERE (AFSSAPS, VENDARGUES, France)
11:25 Desorption Atmospheric Pressure Photoionization in Routine Analysis of Confiscated Drug Samples
Tina KAUPPILA (UNIVERSITY OF HELSINKI, Helsinki, Finland)
11:45 Selective Analysis of Pharmaceuticals in Environmental Water Samples Using Restricted Access Media-Molecularly Imprinted Polymer
Jun HAGINAKA (MUKOGAWA WOMEN'S UNIVERSITY, Hyogo, Japan)
12:05 Occurrence of Veterinary Pharmaceuticals in the Aquatic Environment in Flanders
KELLY SERVAES (VITO NV, MOL, Belgium)
11:05 A Microfluidic Capillary System for Immunoaffinity and Molecular Imprinted Polymer Separations applied to Bioanalysis
Thomas KARNES (VIRGINIA COMMONWEALTH UNIVERSITY, Richmond, Virginia, United States)
11:25 High Performance Microscale Electrophoresis of Biogenic Compounds Using On-Line Sample Concentration Techniques
Koji OTSUKA (KYOTO UNIVERSITY, Kyoto, Japan)
11:45 Cytotoxicity Tests with 5-fluorouracil in a Microanalytical System
Elzbieta JEDRYCH (WARSAW UNIVERSITY OF TECHNOLOGY, Warsaw, Poland)
12:05 Nano Liquid Chromatography Tandem Mass Spectrometry for the Monitoring of Hippocampal Neuropeptides Possibly Involved in Limbic Epilepsy
Ann VAN EECKHAUT (FREE UNIVERSITY OF BRUSSELS (VUB), Brussels, Belgium)
12:25 Lunch & Exhibition
12:45 Thermo Fisher Scientific Workshop
13:30 Poster Session (Group 2)
Parallel Session A: Session 9 Parallel Session B: Session 10
(Aula R - Room R001)
15:30 Total Error as Natural Decision Criteria for Analytical Methods Validation and Transfer
Eric ROZET (UNIVERSITY OF LIEGE, Liege, Belgium)
16:00 Simultaneous Quantification of 10 Cytotoxic Drugs by a Validated LC-ESI-MS/MS Method
Susanne NUSSBAUMER (HÔPITAUX UNIVERSITAIRE DE GENÈVE HUG - PHARMACY, Geneva 14, Switzerland)
16:20 Frictional Heating Effects on Scaling of HPLC/VHPLC Methods
David LLOYD (BRISTOL-MYERS SQUIBB, New Brunswick, United States)
16:40 The Role of Degradant Profiling in Active Pharmaceutical Ingredients and Drug Products
Sara VRIELYNCK (JOHNSON & JOHNSON, Beerse, Belgium)
(Aula R - Room R002)
15:30 MALDI Imaging for Small Molecules and Clinical Proteomics: Developments and Applications
Jonathan STAUBER (IMABIOTECH, Villeneuve d’Ascq, France)
16:00 Micropillar Array Electrospray Ionization Microchip – What is it good for?
Raimo KETOLA (UNIVERSITY OF HELSINKI, Helsinki, Finland)
16:20 Improving MS identification of Bacillus subtilis ΔprpE and 168 proteins with the use of QSRR-based peptides retention times prediction in RP-HPLC
Katarzyna MACUR (MEDICAL UNIVERSITY OF GDANSK, Gdansk, Poland)
16:40 Optimization of Big Protein Sequence Recovery by LC-QTOF for the Future Study of its Posttranslational Modifications.
Cédric DELPORTE (UNIVERSITÉ LIBRE DE BRUXELLES, Bruxelles, Belgium)
19:30 Banquet in "Art Nouveau Zaal" Horta
24/09/2010
(Aula Rector Dhanis)
09:00 Application of Solid Phase Microextraction to Drug Development and Biomarker Discovery
Janusz PAWLISZYN (UNIVERSITY OF WATERLOO, Waterloo Ontario, Canada)
09:40 Break
Parallel Session A: Session 11 Parallel Session B: Session 12
(Aula R - Room R001)
09:45 Aptamer-based Sorbents as an Alternative to Immunosorbents and Molecularly Imprinted Polymers for Selective Extraction of Drugs from Biological Samples
Valerie PICHON (ESPCI, Paris, France)
10:15 Coffee Break and exhibition
11:30 Evaluation of an in-capillary Approach to Perform Quantitative CYP450 Activity Studies
Juan BRAVO (UNIVERSITY OF GENEVA, Geneva, Switzerland)
11:50 Tyrosinase immobilized magnetic nanobeads for the Amperometric Assay of Enzyme Inhibitors: Application to the Skin Whitening Agents
Veronica SIMA HARCEAGA (IULIU HATIEGANU UNIVERSITY, Cluj-Napoca, Romania)
12:10 A Direct-Injection Mekc Method For Drug Analysis in the Presence of Matrix Proteins
Hermann WÄTZIG (TECHNICAL UNIVERSITY BRAUNSCHWEIG, Braunschweig, Germany)
(Aula R - Room R002)
09:45 Proteomics in Drug Analysis
Peter VERHAERT (DELFT UNIVERSITY OF TECHNOLOGY, Delft, The Netherlands)
10:15 Coffee Break and exhibition
11:30 Camptothecin and Thio-camptothecin: the Role of Sulfur in Shifting the Hydrolysis Equilibrium Towards the Closed Lactone form
Carlo BERTUCCI (UNIVERSITY OF BOLOGNA, Bologna, Italy)
11:50 Polymeric Monolithic Ion-exchange Stationary Phases in Combination with pH Gradient for the Separation and Purity Profiling of Monoclonal Antibodies
Mohammad TALEBI (UNIVERSITY OF TASMANIA, Hobart, Australia)
12:10 Functional Quality of Peptides in Pharmaceutical R&D
Sylvia VAN DORPE (GHENT UNIVERSITY, Gent, Belgium)
12:30 Lunch and Exhibition
13:30 Proteomic Biomarker Discovery: From Hypervariable Data to Biomarker Candidates
Rainer BISCHOFF (UNIVERSITY OF GRONINGEN, Groningen, The Netherlands)
14:10 Peptide and Oligonucleotides Aptamers as New Ligands for Analytical Chemistry
Marco MASCINI (UNIVERSITÀ DEGLI STUDI DI FIRENZE, Sesto Fiorentino, Italy)
14:45 Closing Remarks
15:00 Announcements
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