8 vendor seminars will be organised during the lunch breaks on Monday and Tuesday. Participants are invited to register for the vendor seminar of their interest directly by accessing their on-line registration under the menu 'My Registration'. Registration is free of charge but the number of available places is limited.
For registered participants, lunch will be offered directly in the seminar rooms.
Monday, October 1 | 12:45 - 13:45
NOVASEP Seminar: Latest Advances in Purification Processes | Room 211 (level +2)
Presented by: C. Morey and J. Seok Hur
Novasep is a provider of purification systems serving a large range of markets and applications, from low pressure systems to SFC, and from batch to continuous processes. This workshop will present the latest technological advances in purification with a particular focus on SFC and HPLC. Recent developments done in optimizing the different features of these systems, which include PAT, robustness, system reliability, and smart fraction collection control, will be detailed.
PHENOMENEX Seminar: Introducing the Concept of Ultra-High-Performance in Preparative Chromatography Applications…Breaking with Tradition | Room 212 (level +2)
Presented by: M. Jacob, G. Krautz
Column performance is affected by the column hardware, the design of the packing process as well as the efficiency and selectivity of the stationary phase. As a worldwide innovator of top-quality separation devices, Phenomenex delivers preparative chromatographers significant improvements in column lifetime. Award-winning Axia™ technology eliminates column failure due to bed collapse with efficiencies and peak symmetries on par with analytical separations.The seminar features a selection of new ultra performance chromatography media in combination with Axia™ technology.
KNAUER / CHROMACON Seminar: Contichrom® – A New Dimension in Purification | Room 213 (level +2)
Presented by: M. Luebbert, G. Stroehlein
Contichrom® lab is a preparative 2-column liquid chromatography system designed for discovery, process development and scale-up, offering great flexibility for all process choices (batch, SMB, MCSGP, other multi-column) using a single equipment and software for biologics and synthetic APIs.
The MCSGP process principle uses twin columns, whereby the impure side fractions containing product are recycled internally extracting all product, thereby increasing both yield and purity by 50% at a 10-fold throughput increase and 70% buffer reduction.
Contichrom® lab has been designed to be very user-friendly employing software that helps the user to navigate through the process setup, execution and reporting, being 21CFR part 11 compliant.
The workshop will explain the uses, application fields as well as the process principles.
WATERS Seminar: From Screening with Sub-2 µm Particles to Preparative Separation - Scaling Up from Generic UPLC and UPC˛ Methods | Room 214 (level +2)
Presented by: S. Dubant
The use of small particles columns for analytical purposes has kept expanding since the introduction of UPLC in 2004 and is now reaching the realm of SFC with the recent introduction of UPC˛. During this workshop, we will discuss how sub-2 µm column chemistry and UPLC and UPC˛ technologies can be used as very fast and efficient solutions to produce successful preparative conditions for purification purposes.
Tuesday, October 2 | 12:15 - 13:15
AKZO NOBEL SEPARATION PRODUCTS / KROMASIL Seminar: Altering Elution Behaviour by Switching Stationary and Mobile Phase Parameters | Room 211 (level +2)
Presented by: R. Fredriksson, K. Hallman
This workshop describes how the elution behaviour can be altered by switching several chromatographic parameters. The importance of the stationary phase, mobile phase constituents and pH and how they can affect the adsorption isotherms will be shown. Furthermore, several case studies will show how the elution behaviour affects important parameters such as yield, purity and productivity.
MERCK MILLIPORE Seminar: New High Quality Phase for Downstream Evaluated in Continuous Chromatography | Room 212 (level +2)
Presented by: R. Skudas, A. Schwämmle
The development of peptide based drugs is increasingly gaining importance in the pharmaceutical industry. One of the most relevant challenges in producing peptide drugs in a cost-effective way is the chromatographic purification process.
With the newly introduced PharmPrep® P product line, Merck-Millipore is providing high quality stationary phases which perfectly meet the demands of peptide manufacturers with respect to purification performance, efficiency, and cost-effectiveness. This presentation will highlight the application range of normal-phase, reversed-phase, and ion-exchange media in the downstream processing of peptides and small proteins.
In addition we introduce results of real case studies where we evaluated continuous chromatography, exploring the potential of economic efficiency in affinity, ion exchange and reversed phase chromatography modes.
CHIRAL TECHNOLOGIES EUROPE Seminar: Preparative Chiral Separations | Room 213 (level +2)
Presented by: P. Franco
An overview of the approach used at Chiral Technologies to screen and separate chiral molecules at preparative scale. Solubility, stability, and scale will be reviewed in addition to our approach to resolve common issues. Our approach to scalability and selection between batch and continuous systems will be presented.
PIC-SOLUTION Seminar: Recent Developments in Preparative SFC | Room 214 (level +2)
The purpose is to introduce the PIC Solution range of analytical and preparative SFC systems and to highlight some aspects of their performance. The seminar will focus on:
- CO2 recycle. A major advantage of the use of preparative SFC is the reduction in costs due to the use of CO2 in place of much of the organic solvents used in HPLC. PIC Solution’s CO2 recycle is a compact component of the SFC unit, allowing recovery of up to ~95% of the CO2.
- Performance of the Hybrid analytical / preparative SFC system. The compromises in construction of a system comprising both analytical and preparative channels in a compact skid are discussed and the performance characteristics of the SFC-PICLab Hybrid 10-100 system described.
- Collection Manager. The Collect Manager is a real-time solution for fraction collection and stacked
injection set-up and management.
- Sample injection. Injection systems for preparative SFC are reviewed and data on the performance of the different possible injection techniques for the PICLab SFC systems will be discussed.