SPICA 2012
Lectures confirmed to date
 Quality by Design in API Purifications. Making the Right Things
Dr Alessandro BUTTE
(ETH ZURICH, Zurich, Switzerland)
 Molecular Modeling of the Affinity Chromatography of Proteins: Status and Perspectives
Prof. Carlo CAVALLOTTI
(POLITECNICO DI MILANO, Milano, Italy)

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 Molecular Engineering of Multiple Weak Interactions for High Selectivity Bioseparations
Prof. Steven CRAMER M
(RENSSELAER POLYTECHNIC INSTITUTE, Troy, United States)

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 Implementation of a Continuous Chromatography Step in The Synthesis of an API – Combining Chemistry and Chromatography to Achieve Better Economics
Dr Olivier DAPREMONT
(AMPAC FINE CHEMICALS, Rancho Cordova, United States)

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 New Approaches to Food Fractionation by Chromatography: Adapting High-Cost Techniques to the Production of Moderate-Value Products
Prof. Conan FEE
(UNIVERSITY OF CANTERBURY, Christchurch, New Zealand)

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 Biological Production of Peptides
Prof. Susanna LEONG
(NANYANG TECHNOLOGICAL UNIVERSITY, Singapore, Singapore)

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Oral Communications
 Purification of Proteins from Human Blood Plasma by Multicolumn Solvent Gradient Purification
Mr Daniel BAUR
(ETH ZÜRICH, Zurich, Switzerland)
 Distributed Pore Surface Model
Ing Niklas BORG
(LUND UNIVERSITY, Lund, Sweden)
 Towards Optimally Sized Centrifugal Partition Chromatography Columns - Process Design Methodology and Applications
Mr Sebastien CHOLLET
(GEPEA LABORATORY, Saint-Nazaire, France)
 A Model Based Approach to Reducing the Analytical Burden of High Throughput Screening
Dr Marcus DEGERMAN
(LUND UNIVERSITY, Lund, Sweden)
 Liquid-Liquid Extraction of Biomolecules - Process Development and Integration into Downstream Processing
Mr Jan Kristof EGGERSGLUESS
(CLAUSTHAL UNIVERSITY OF TECHNOLOGY, Clausthal, Germany)
 Characterization of Adsorption in SFC: an Evaluation of Methods Used in LC
Prof. Torgny FORNSTEDT
(KARLSTAD UNIVERSITY, Karlstad, Sweden)
 New Trend in Material Development for Peptide Purification
Dr Nicola FORRER
(ZEOCHEM, Uetikon am See, Switzerland)
 Preparative Chiral Chromatography: What Can Go Wrong and How to Solve it
Dr Pilar FRANCO
(CHIRAL TECHNOLOGIES, INC, Illkirch, France)
 From Racemate to Single Enantiomer with 100% Yield by Process Integration of SMB and Enzymatic Racemization
Mr Markus FUEREDER
(ETH ZURICH, Basel, Switzerland)
 Modeling Protein Adsorption Equilibria on Ion-Exchange Resins
Dr Bertrand GUELAT
(NOVARTIS PHARMA AG, Basel, Switzerland)
 Quality by Design with Rigorous Process Modeling as Platform Technology of the Future
Mr Christoph HELLING
(CLAUSTHAL UNIVERSITY OF TECHNOLOGY, Clausthal-Zellerfeld, Germany)
 Experimental Study on a Binary Chromatographic System Subject to a Mixed Competitive-Cooperative Adsorption Isotherm
Mr Simon JERMANN
(ETH ZÜRICH, Zurich, Switzerland)
 Separation of Bionanoparticles and Biological Superstructures
Prof. Alois JUNGBAUER
(UNIV AGRICULTURAL SCIENCES, Vienna, Austria)
 Integrated Chromatographic Processes for the Production of Pure Enantiomers
Prof. Malte KASPEREIT
(FRIEDRICH-ALEXANDER UNIVERSITY ERLANGEN-NUREMBERG, Erlangen, Germany)
 Model Mismatch Resolution and Optimization for Simulated Moving Bed and Continuous Chromatographic Processes
Prof. Yoshiaki KAWAJIRI
(GEORGIA INSTITUTE OF TECHNOLOGY, Atlanta, United States)
 A Non-Conventional Application of Simulated Moving Bed Technology: Purification of a Complex Mixture
Ms Kiara KOCHENDOERFER
(BASF SE, Ludwigshafen, Germany)
 Model Based Design and Integration of Crystallization Processes of Natural Products in Down Stream Processing
Mr Iraj KOUDOUS
(INSITUT FÜR THERMISCHE VERFAHRENS- UND PROZESSTECHNIK, Clausthal-Zellerfeld, Germany)
 Continuous Synthesis and Purification Through Direct Combination of a Flow Reactor and Simulated Moving Bed Chromatography
Dr Ju Weon LEE
(MAX-PLANCK-INSTITUTE FOR DYNAMICS OF COMPLEX TECHINCAL SYSTEMS, Magdeburg, Germany)
 Nanofiltration of Peptides in Acetonitrile/Water Mixtures: Process Development
Ms Patrizia MARCHETTI
(LONZA, Visp, Switzerland)
 Continuous Purification of Single-Chain Antibody Fragments by Simulated Moving Bed Chromatography
Mr Carlos Andres MARTINEZ CRISTANCHO
(MAX-PLANCK-INSTITUT MAGDEBURG, Magdeburg, Germany)
 Design Of Tailor-Made Stationary And Mobile Phase In Liquid-Liquid Chromatography
Prof. Mirjana MINCEVA
(TECHNICAL UNIVERSITY OF MUNICH, Freising, Germany)
 Relay SMB: A Simple and Efficient Way of Implementing Simulated Moving-Bed Chromatography
Prof. José Paulo MOTA
(UNIVERSIDADE NOVA DE LISBOA, Caparica, Portugal)
 Enabling High Purities and Yields in Therapeutic Peptide Purification by Using Continuous Chromatography (MCSGP)
Dr Thomas MÜLLER-SPÄTH
(CHROMACON AG, Zurich, Switzerland)
 Efficient API Purification or How Combining OSN and Chromatography Increases Your Process Yields!
Dr Muriel NASSO
(EVONIK, Wembley, United Kingdom)
 Modeling of Protein Aggregation in Preparative Chromatography
Prof. Bernt NILSSON
(LUND UNIVERSITY, Lund, Sweden)
 Peptidomimetic Affinity Ligands (PALs) - A Powerful Approach to Improving DSP Performance
Dr Matthias PASCHKE
(3B PHARMACEUTICALS GMBH, Berlin, Germany)
 Shifting the Scale-up Limits of Disposable Downstream Processing
Mr. Marcel RAEDTS
(PROXCYS BV, Nieuw Amsterdam, The Netherlands)
 Optimization of Simulated Moving Bed Processes for Multicomponent Chiral Separations
Dr António E. RIBEIRO
(POLYTECHNIC INSTITUTE OF BRAGANÇA, Bragança, Portugal)
 Supercritical Fluids as the Desorbent for Simulated Moving Bed? Application to the Concentration of Triterpenoids from Taiwanofugus Camphorate
Ms Liang RU CHIEN
(I SHOU UNIVERSITY, Kaohsiung City, Taiwan)
 Chromatographic Process Options for Reduced Purities
Prof. Tuomo SAINIO
(LAPPEENRANTA UNIVERSITY OF TECHNOLOGY, Lappeenranta, Finland)
 Study of Hydrodynamics in Chromatographic Columns by Computed X-Ray Tomography and its Evaluation by CFD Simulations
Ms Irma SCHMIDT
(UNIVERSITY ERLANGEN-NUREMBERG, Erlangen, Germany)
 Scalable Technology for the Extraction of Pharmaceuticals (STEP): Progress on Developing Versatile Small Footprint Technology for Continuous Processing at the Lab Scale up to 1 Kg/Day
Prof. Ian SUTHERLAND
(BRUNEL INSTITUTE FOR BIOENGINEERING, Uxbridge, United Kingdom)
Dr Svetlana IGNATOVA
(BRUNEL UNIVERSITY, Uxbridge, United Kingdom)
 A Reaction-Separation Integrated Process for the High-Yield Synthesis of Rare Sugars
Ms Nina WAGNER
(ETH ZURICH D-BSSE, Basel, Switzerland)
 Integration of Hydrophobic Interaction- and Ion Exchange Chromatography
Mr Tim WELLSANDT
(INSITUT FÜR THERMISCHE VERFAHRENS- UND PROZESSTECHNIK, Clausthal-Zellerfeld, Germany)
 A New Disposable Technology for Chromatographic Purification of Biopharmaceuticals
Dr David YAVORSKY
(MERCK-MILLIPORE, Bedford, United States)
Workshops
 From Development to Commercial Scale: Rules to Scale up, QbD, Regulatory, Process Validation
Dr Alessandro BUTTE
(ETH ZURICH, Zurich, Switzerland)

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 Process Design for Purification of Biomolecules
Prof. Alois JUNGBAUER
(UNIV AGRICULTURAL SCIENCES, Vienna, Austria)
 Multicolumn Processes: from Historical SMB to the Latest Advances in the Purification of Biomolecules
Prof. Arvind RAJENDRAN
(UNIVERSITY OF ALBERTA, Edmonton, AB, Canada)
 Preparative HPLC : Phase Screening, Method Optimization, Process Development. Troubleshooting a Preparative Chromatographic Device
Dr Michael SCHULTE
(MERCK, Darmstadt, Germany)
 Process Design for Purification of Small Molecules
Prof. Jochen STRUBE
(CLAUSTHAL UNIVERSITY OF TECHNOLOGY, Clausthal-Zellerfeld, Germany)
 Solving a Purification Process: Choice of the Appropriate Process (Batch vs Continuous, Low Pressure vs High Pressure, Liquid vs SFC, Centrifugal Partition Chromatography vs Countercurrent Chromatography)
Dr Eric VALERY
(NOVASEP, Pompey, France)
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